These concical adapters are KF-50 to CF 4-1/2 inches with flange sizes that follow ISO-KF NW-50 to ConflatŪ CFF 4.50 standards. They are commonly used to make connections between ISO-KF and ConflatŪ vacuum fittings. The ISO-KF flanges are often called quick flange fittings because they are quick to assemble. A circumferential clamp and centering ring form the vacuum seal between the connecting flanges (please see top right figure - click to enlarge). The centering ring contains a rubber elastomer o-ring. The standard sizes for quick flange fittings are KF-10, KF-16, KF-25, KF-40, and KF-50 with flange sizes NW-10, NW-16, NW-25, NW-40, and NW-50, respectively. They are made of corrosive resistant stainless steel. ConflatŪ is a registered trademark of Varian Corporation.